Title
Tricyclic Antidepressants for Autism Spectrum Disorders (ASD) in Children and Adolescents
Author
Romy Hurwitz; Roger Blackmore; Philip Hazell; Katrina Williams; Susan Woolfenden
Summary
This web page summarizes a research review conducted to determine whether tricyclic antidepressants (TCAs) can be used to treat autism symptoms, as well as challenging behaviors and co-occurring mental health conditions in autism.
The review found three studies using two TCAs (tianeptine and clomipramine) with people on the autism spectrum. Evidence of positive impacts was limited and sometimes contradictory, and side effects were reported. The page concludes that more research is required before TCAs can be recommended for use with people on the autism spectrum.
"The Cochrane Library (ISSN 1465-1858) is a collection of databases that contain high-quality, independent evidence to inform healthcare decision-making. The Cochrane Library is owned by Cochrane and published by Wiley."[Website]
Language
English
Subjects
Evaluating Research & Information
Mental Health
Publisher
Cochrane Database of Systematic Reviews
DateModified
12/30/2023 10:25 AM EST